Category: ARTICLES, APPNOTES, FAQ
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How do retention and efficiency of asymmetric dimethylarginine ADMA compare using 4um vs 2.o Diamond Hydride columns - AppNote
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How to choose a suitable mobile phase additive for negative ionization mode LCMS - Tips & Suggestions
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How to eliminate retention time drift in LCMS with Aqueous Normal Phase ANP methods - Tips & Suggestions
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How to improve peak shapes, retention & carryover for polar compounds with the Cogent Diamond Hydride™ column - Tips & Suggestions
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How to prepare 10mM ammonium acetate buffer 90:10 in acetonitrile for HPLC and LCMS - Tips & Suggestions
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How to prepare 16mM ammonium acetate buffer 90:10 in acetonitrile for HPLC - Tips & Suggestions
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I am not observing any peaks for succinic acid or alpha-ketoglutarate with the Cogent Diamond Hydride column - Tips & Suggestions
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Injection Technique for Aqueous Samples using Cogent TYPE-C Columns in ANP - Tips & Suggestions
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Is TYPE-C Silica a high purity support and have a low metal content silica like Type B silica - FAQ
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Issues arising from changes in mobile phase with acids to one with ammonium salts. Tips & Suggestions
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LFER studies compared to Log D data in describing the Aqueous Normal Phase ANP retention - Tips & Suggestions
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Lower retention is observed when functional group in a compound is ionized - Tips & Suggestions
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Mobile Phase recommendation Cogent Diamond Hydride columns for use with serum samples in Aqueous Normal Phase LCMS - Tips & Suggestions
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Modify selectivity in an ANP method of HPLC using different mobile phase pH - Tips & Suggestions
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My method uses an standard type-B silica based HPLC column is there a Cogent TYPE-C column equivalent substitute - FAQ
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Peaks are broad and non symmetrical in LCMS method using Reversed Phase columns - Tips & Suggestions
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Restoring the initial results with a method for analyzing AMP ADP ATP UDP and GPT in biological extracts - Tips & Suggestions
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Solvents and solutions that should be avoided when using PEEK filters fittings or tubing - Tech Information
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Solving baseline problems in ANP methods with the Cogent Diamond Hydride column - Tips & Suggestions
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The best way to avoid with ion suppression issues in LCMS if you need to use an ion-pair agent - Primer
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Troubleshooting problems with poor HPLC runs before the examining the column - Tips & Suggestions
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Two gradients to use for analysis of hydrophilic and or hydrophobic molecules in the same Aqueous Normal Phase ANP method - Tips & Suggestions
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Understanding some of the differences between HILIC columns and TYPE-C columns - Tips & Suggestions
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Use a low concentration of salt in your mobile phase to avoid ion suppression and build up on your inlet source - Tips & Suggestions
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Using ammonium acetate or formate in an acetonitrile based HPLC mobile phase for Aqueous Normal Phase ANP - Tips & Suggestions
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Using an Aqueous Normal Phase ANP method will sodium ions interfere with succinate when analyzing sodium succinate - FAQ
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Using temperature changes for separations of terpenoids with the Cogent Bidentate C18 and UDC-Cholesterol HPLC columns - Tips & Suggestions
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Using triethylamine TEA in Aqueous Normal Phase ANP methods for simple sugars - Tips & Suggestions
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What are some notable examples of journal articles that feature Aqueous Normal Phase ANP methods in metabolomics studies - FAQ
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What are the main differences between Cogent Amide columns and other brands of Amide - FAQ
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What is the most effective way to clean HPLC columns after or before use - Tips & Suggestions
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What pressure should I expect with a Diamond Hydride 2.o HPLC column at flow rates from 0.2 to 2.0mL / min - FAQ
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What special care should I take to protect my HPLC columns when I am equilibrating them - FAQ
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Which acid or base additive should I choose for positive or negative ion mode in LC-MS - FAQ
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Which Cogent TYPE-C column do you recommend for the separation of positional isomers by HPLC or LCMS - FAQ
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Which column do you suggest for Cocaine & metabolite Ecognin separation - Tips & Suggestions
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Why does the metal content of a silica particle contribute to the peak shape of my chromatogram in HPLC - FAQ
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